Jing-Dong Jackie Han

Professor, Center for Quantitative Biology, Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University

Professional profile

Prof. Jing-Dong Jackie Han is a distinguished scientist currently serving as a Professor at the Center for Quantitative Biology, Peking-Tsinghua Center for Life Sciences, and the Academy for Advanced Interdisciplinary Studies at Peking University, Beijing. Professor Han's research focuses on the structure and dynamic inference of molecular networks, utilising a combination of large-scale experiments and computational analysis to explore their design principles. Her work aims to understand how complex phenotypes, such as ageing, cancer, and stem cell development, are regulated through these networks. Her research spans computational and systems biology of development and ageing, artificial intelligence (AI) for ageing measurement and anti-ageing intervention target discovery, and the development of computational algorithms for data integration and network analysis.

Her primary goal is to use ageing clocks and quantitative models based on 3D and infrared facial images, as well as human single-cell peripheral blood data, combined with AI algorithms, molecular biology, cell biology, and systems biology approaches, to identify ageing. Through these models, she has discovered modulators, such as metabolic small molecules and long non-coding RNAs (lncRNAs), that have the potential to serve as human anti-ageing interventions.