Péter Horváth
Director, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged
Leader, Lendület Laboratory of Microscopic Image Analysis and Machine Learning, HUN-REN BRC
Dr Péter Horváth is the Director of the Institute of Biochemistry at the HUN-REN Biological Research Centre (BRC) in Szeged. He leads the Lendület Laboratory of Microscopic Image Analysis and Machine Learning, focusing on computational solutions to biological problems by integrating wet-lab techniques, light microscopy, image analysis, and machine learning methods.
Deep Visual Proteomics (DVP), a cell characterisation method developed by his team, combines AI-driven image analysis with laser microdissection microscopy and high-sensitivity mass spectrometry. DVP involves capturing high-resolution images of tumour tissue samples, using machine learning algorithms to identify cells with abnormal morphology, excising them with precision lasers, and conducting comprehensive protein analyses through mass spectrometry.
Leveraging DVP technology, Dr Horváth established the Single Cell Centre at BRC, supported by the Chan Zuckerberg Foundation, the EU's Human Cell Atlas projects, and the Human Cell Atlas consortium. The centre employs an automated system that processes samples from receipt to single-cell extraction, utilising barcode technology to trace each cell's history. Collaborations with leading international institutions, including the laboratories of Matthias Mann in Munich and Copenhagen, further enhance the centre's molecular analyses.
His research aims to elucidate fundamental biological questions, such as tumour development, metastasis, and cellular changes during division, focusing on tumour tissues from patients with breast, lung, and melanoma cancers.